Application
Western blot analysis of ELMO1 Antibody (Center) in Ramos cell line lysates (35ug/lane). ELMO1 (arrow) was detected using the purified Pab.Application
ELMO1 Antibody (Center) flow cytometry analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | ELMO1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ELMO1; KIAA0281; Engulfment and cell motility protein 1; Protein ced-12 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0281 |
|---|---|
| Alternative Names | ELMO1 KIAA0281 Engulfment and cell motility protein 1 Protein ced-12 homolog |
| Molecular Weight(MW) | 83829 Da |
| Function | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 |
| Tissue Specificity | Widely expressed, with a higher expression in the spleen and placenta |
| Cellular Localization | Cytoplasm. Cell membrane. Note=Translocation to plasma membrane seems to be mediated by DOCK1 and CRK |
| Entrez Gene | 9844 |
|---|
Application
Western blot analysis of ELMO1 Antibody (Center) in Ramos cell line lysates (35ug/lane). ELMO1 (arrow) was detected using the purified Pab.
Application
ELMO1 Antibody (Center) flow cytometry analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
