Application
ENC1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ENC1 antibody detected the ENC1 protein (arrow).| Product Name | ENC1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ENC1; KLHL37; NRPB; PIG10; Ectoderm-neural cortex protein 1; Kelch-like protein 37; Nuclear matrix protein NRP/B; p53-induced gene 10 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KLHL37 NRPB PIG10 |
|---|---|
| Alternative Names | ENC1 KLHL37 NRPB PIG10 Ectoderm-neural cortex protein 1 Kelch-like protein 37 Nuclear matrix protein NRP/B p53-induced gene 10 protein |
| Molecular Weight(MW) | 66130 Da |
| Function | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin- mediated proteasomal degradation mechanism |
| Tissue Specificity | Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas. May be down- regulated in neuroblastoma tumors |
| Cellular Localization | Nucleus matrix. Cytoplasm. Cytoplasm, cytoskeleton |
| Entrez Gene | 8507 |
|---|---|
| Nucleotide Accession | NP_003624.1 |
Application
ENC1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ENC1 antibody detected the ENC1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
