Application
Western blot analysis on (A) Fetal liver lysates (B) Hela and (C) LNCaP lysates using anti-ENTPD5 RabMAb (Cat. #AJ1262a).| Product Name | ENTPD5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3738 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000~5000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD39L4, PCPH |
|---|---|
| Alternative Names | ENTPD5 CD39L4 PCPH Ectonucleoside triphosphate diphosphohydrolase 5 Nucleoside diphosphatase CD39 antigen-like 4 ER-UDPase |
| Molecular Weight(MW) | 47517 Da |
| Function | Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling (By similarity) |
| Tissue Specificity | Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues |
| Cellular Localization | Endoplasmic reticulum membrane (By similarity); Single-pass type II membrane protein (By similarity) |
| Entrez Gene | 957 |
|---|
Application
Western blot analysis on (A) Fetal liver lysates (B) Hela and (C) LNCaP lysates using anti-ENTPD5 RabMAb (Cat. #AJ1262a).| Application Notes | WB:1:1000~5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
