Application
EPN1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the EPN1 antibody detected the EPN1 protein (arrow).| Product Name | EPN1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | EPN1 Epsin-1 EH domain-binding mitotic phosphoprotein EPS-15-interacting protein 1 |
|---|---|
| Molecular Weight(MW) | 60293 Da |
| Function | Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis |
| Tissue Specificity | This EPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-232 amino acids from the Central region of human EPN1. |
| Cellular Localization | Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein (By similarity). Nucleus (By similarity). Membrane, clathrin-coated pit (By similarity) Note=Associated with the cytoplasmic membrane at sites where clathrin-coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145 (By similarity) |
| Entrez Gene | 29924 |
|---|---|
| Nucleotide Accession | NP_037465.2 NP_001123544.1 NP_001123543.1 |
Application
EPN1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the EPN1 antibody detected the EPN1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
