Application
A. Western blot analysis on (A) HeLa (B) 293T and (C) SHSY5Y cell lysates using anti-EPS15R RabMAb (Cat. #AJ1266b), dilution 1:20,000.| Product Name | EPS15R Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1146Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:10000~50000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EPS15R |
|---|---|
| Alternative Names | EPS15L1 EPS15R Epidermal growth factor receptor substrate 15-like 1 Eps15-related protein |
| Molecular Weight(MW) | 94255 Da |
| Function | Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2 |
| Tissue Specificity | A synthetic peptide corresponding to residues near the N-terminus of human EPS15R was used as an immunogen. |
| Cellular Localization | Cell membrane; Peripheral membrane protein (By similarity). Nucleus (By similarity). Membrane, coated pit (By similarity). Note=Localized to plasma membrane coated pits (By similarity) |
| Entrez Gene | 58513 |
|---|
Application
A. Western blot analysis on (A) HeLa (B) 293T and (C) SHSY5Y cell lysates using anti-EPS15R RabMAb (Cat. #AJ1266b), dilution 1:20,000.| Application Notes | WB:1:10000~50000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
