Application
The anti-EPS15R Pab is used in Western blot to detect EPS15R in Y79 cell lysate.| Product Name | EPS15R Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EPS15R |
|---|---|
| Alternative Names | EPS15L1 EPS15R Epidermal growth factor receptor substrate 15-like 1 Eps15-related protein |
| Molecular Weight(MW) | 94255 Da |
| Function | Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2 |
| Tissue Specificity | This EPS15R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193~222 amino acids from the N-terminal region of human EPS15R. |
| Cellular Localization | Cell membrane; Peripheral membrane protein (By similarity). Nucleus (By similarity). Membrane, coated pit (By similarity). Note=Localized to plasma membrane coated pits (By similarity) |
| Entrez Gene | 58513 |
|---|
Application
The anti-EPS15R Pab is used in Western blot to detect EPS15R in Y79 cell lysate.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
