Application
ERAP2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ERAP2 antibody detected the ERAP2 protein (arrow).Application
ERAP2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ERAP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | ERAP2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LRAP |
|---|---|
| Alternative Names | ERAP2 LRAP Endoplasmic reticulum aminopeptidase 2 Leukocyte-derived arginine aminopeptidase |
| Molecular Weight(MW) | 110462 Da |
| Function | Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys |
| Tissue Specificity | Ubiquitously expressed. Highly expressed in spleen and leukocytes |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
| Entrez Gene | 64167 |
|---|---|
| Nucleotide Accession | NP_001123612.1 |
Application
ERAP2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ERAP2 antibody detected the ERAP2 protein (arrow).
Application
ERAP2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ERAP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
