Application
ERCC3 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ERCC3 antibody detected the ERCC3 protein (arrow).| Product Name | ERCC3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | XPB, XPBC |
|---|---|
| Alternative Names | ERCC3 XPB XPBC TFIIH basal transcription factor complex helicase XPB subunit Basic transcription factor 2 89 kDa subunit DNA excision repair protein ERCC-3 DNA repair protein complementing XP-B cells TFIIH basal transcription factor complex 89 kDa s |
| Molecular Weight(MW) | 89278 Da |
| Function | ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage |
| Tissue Specificity | This ERCC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-62 amino acids from the N-terminal region of human ERCC3. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 2071 |
|---|---|
| Nucleotide Accession | NP_000113.1 |
Application
ERCC3 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ERCC3 antibody detected the ERCC3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
