Application
ERCC5 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ERCC5 antibody detected the ERCC5 protein (arrow).| Product Name | ERCC5 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ERCM2, XPG, XPGC |
|---|---|
| Alternative Names | ERCC5 ERCM2 XPG XPGC DNA repair protein complementing XP-G cells DNA excision repair protein ERCC-5 Xeroderma pigmentosum group G-complementing protein |
| Molecular Weight(MW) | 133108 Da |
| Function | Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too |
| Tissue Specificity | This ERCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1150-1178 amino acids from the C-terminal region of human ERCC5. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 2073 |
|---|---|
| Nucleotide Accession | NP_000114.2 |
Application
ERCC5 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the ERCC5 antibody detected the ERCC5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
