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EREG Antibody (C-term)

Catalog Number:OM232424
OM232424
Discount Price
OM232424-100ul
1~2 Week
100ul
OM232424-50ul
50ul
OM232424-20ul
20ul
1~2 Week
Product Profile
Product Name EREG Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names EREG
Proepiregulin
Epiregulin
Molecular Weight(MW) 19044 Da
Function Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis
Tissue Specificity In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon
Cellular Localization Epiregulin: Secreted, extracellular space.
Database Links
Entrez Gene 2069
Application

Application

Western blot analysis of EREG Antibody (C-term) in HepG2 cell line lysates (35ug/lane). EREG (arrow) was detected using the purified Pab.

Application

EREG Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the EREG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

EREG Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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