Application
ERF3B Antibody (Center) western blot analysis in 293 cell line and mouse stomach tissue lysates (35ug/lane).This demonstrates the ERF3B antibody detected the ERF3B protein (arrow).| Product Name | ERF3B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GSPT2; ERF3B; Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; G1 to S phase transition protein 2 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ERF3B |
|---|---|
| Alternative Names | GSPT2 ERF3B Eukaryotic peptide chain release factor GTP-binding subunit ERF3B G1 to S phase transition protein 2 homolog |
| Molecular Weight(MW) | 68883 Da |
| Function | Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons |
| Tissue Specificity | Highly expressed in IUCC stage II colorectal cancer (CRC) |
| Cellular Localization | Cytoplasm (Probable). |
| Entrez Gene | 23708 |
|---|
Application
ERF3B Antibody (Center) western blot analysis in 293 cell line and mouse stomach tissue lysates (35ug/lane).This demonstrates the ERF3B antibody detected the ERF3B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
