Application
Western blot analysis of ERN2 N-term in mouse stomach tissue lysates (35ug/lane). ERN2 (arrow) was detected using the purified Pab.| Product Name | ERN2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IRE2 |
|---|---|
| Alternative Names | ERN2 IRE2 Serine/threonine-protein kinase/endoribonuclease IRE2 Endoplasmic reticulum-to-nucleus signaling 2 Inositol-requiring protein 2 Ire1-beta Serine/threonine-protein kinase Endoribonuclease |
| Molecular Weight(MW) | 102480 Da |
| Function | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins |
| Tissue Specificity | This ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96~126 amino acids from the N-terminal region of human ERN2. |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein |
| Entrez Gene | 10595 |
|---|
Application
Western blot analysis of ERN2 N-term in mouse stomach tissue lysates (35ug/lane). ERN2 (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
