Application
ERV3 Antibody (C-Term) western blot analysis in 293,HepG2 cell line lysates (35ug/lane).This demonstrates the ERV3 antibody detected the ERV3 protein (arrow).Application
ERV3 Antibody (C-Term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ERV3 Antibody (C-Term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | ERV3 Antibody (C-Term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ERV3 |
|---|---|
| Alternative Names | ERV3-1 ERV3 HERV-R_7q21.2 provirus ancestral Env polyprotein ERV-3 envelope protein ERV3-1 envelope protein Envelope polyprotein HERV-R envelope protein Surface protein Transmembrane protein |
| Molecular Weight(MW) | 67942 Da |
| Function | Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through decrease expression of cyclin B1 and increased expression of p21 in vitro TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity) |
| Tissue Specificity | Expressed at higher level in adrenal, sebaceous glands and placenta. Expressed at lower level in bone marrow, brain, breast, colon, heart, kidney, liver, lung, ovary, PBL, prostate, skin, spleen, testis, thymus, thyroid, trachea |
| Cellular Localization | Virion. |
| Entrez Gene | 2086 |
|---|---|
| Nucleotide Accession | NP_001007254.2 |
Application
ERV3 Antibody (C-Term) western blot analysis in 293,HepG2 cell line lysates (35ug/lane).This demonstrates the ERV3 antibody detected the ERV3 protein (arrow).
Application
ERV3 Antibody (C-Term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ERV3 Antibody (C-Term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
