Application
ESX1 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ESX1 antibody detected the ESX1 protein (arrow).| Product Name | ESX1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ESX1; ESX1L; ESX1R; Homeobox protein ESX1; Extraembryonic, spermatogenesis, homeobox 1; Homeobox protein ESX1-N; Homeobox protein ESX1-C |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ESX1L ESX1R |
|---|---|
| Alternative Names | ESX1 ESX1L ESX1R Homeobox protein ESX1 Extraembryonic spermatogenesis homeobox 1 Homeobox protein ESX1-N Homeobox protein ESX1-C |
| Molecular Weight(MW) | 44297 Da |
| Function | May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover |
| Tissue Specificity | Expressed in placenta and testis. Expressed in testicular germ cell tumors |
| Cellular Localization | Cytoplasm. Nucleus. Note=ESXR1-N localizes specifically to the nucleus while ESXR1-C localizes specifically to the cytoplasm |
| Entrez Gene | 80712 |
|---|---|
| Nucleotide Accession | NP_703149.1 |
Application
ESX1 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ESX1 antibody detected the ESX1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
