Application
Western blot analysis of EVC Antibody (N-term) in K562, MDA-MB435, 293 cell line lysates (35ug/lane). EVC (arrow) was detected using the purified Pab.| Product Name | EVC Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EVC; Ellis-van Creveld syndrome protein; DWF-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | EVC Ellis-van Creveld syndrome protein DWF-1 |
|---|---|
| Molecular Weight(MW) | 111990 Da |
| Function | Acts as a positive mediator of Hedgehog signaling indispensable for normal endochondral growth and skeletal development (By similarity) |
| Tissue Specificity | Found in the developing vertebral bodies, ribs, upper and lower limbs, heart, kidney, lung |
| Cellular Localization | Cell membrane; Single-pass membrane protein (By similarity). Cytoplasm, cytoskeleton, cilium basal body (By similarity). Cell projection, cilium (By similarity). Cell projection, cilium membrane (By similarity). Note=EVC2 is required for the localization of EVC at the base of primary cilia (By similarity) |
| Entrez Gene | 2121 |
|---|
Application
Western blot analysis of EVC Antibody (N-term) in K562, MDA-MB435, 293 cell line lysates (35ug/lane). EVC (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
