Application
F12 Antibody (N-term) western blot analysis in K562(lane 1),CEM(lane 2),MDA-MB435(lane 3) cell line lysates (35ug/lane).This demonstrates the F12 antibody detected the F12 protein (arrow).| Product Name | F12 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | F12; Coagulation factor XII; Hageman factor; Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | F12 Coagulation factor XII Hageman factor Coagulation factor XIIa heavy chain Beta-factor XIIa part 1 Beta-factor XIIa part 2 Coagulation factor XIIa light chain |
|---|---|
| Molecular Weight(MW) | 67792 Da |
| Function | Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta- factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa |
| Tissue Specificity | This F12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13~43 amino acids from the N-terminal region of human F12. |
| Cellular Localization | Secreted. |
| Entrez Gene | 2161 |
|---|
Application
F12 Antibody (N-term) western blot analysis in K562(lane 1),CEM(lane 2),MDA-MB435(lane 3) cell line lysates (35ug/lane).This demonstrates the F12 antibody detected the F12 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
