Application
FADD Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the FADD antibody detected the FADD protein (arrow).| Product Name | FADD (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FADD; MORT1; Protein FADD; Mediator of receptor induced toxicity; FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MORT1 |
|---|---|
| Alternative Names | FADD MORT1 Protein FADD Mediator of receptor induced toxicity FAS-associated death domain protein FAS-associating death domain-containing protein Growth-inhibiting gene 3 protein |
| Molecular Weight(MW) | 23279 Da |
| Function | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling |
| Tissue Specificity | Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes |
| Entrez Gene | 8772 |
|---|---|
| Nucleotide Accession | NP_003815.1 |
Application
FADD Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the FADD antibody detected the FADD protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
