Application
FAIM2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the FAIM2 antibody detected the FAIM2 protein (arrow).| Product Name | FAIM2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FAIM2; KIAA0950; LFG; LFG2; NMP35; TMBIM2; Protein lifeguard 2; Fas apoptotic inhibitory molecule 2; Neural membrane protein 35; Transmembrane BAX inhibitor motif-containing protein 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0950 LFG LFG2 NMP35 TMBIM2 |
|---|---|
| Alternative Names | FAIM2 KIAA0950 LFG LFG2 NMP35 TMBIM2 Protein lifeguard 2 Fas apoptotic inhibitory molecule 2 Neural membrane protein 35 Transmembrane BAX inhibitor motif-containing protein 2 |
| Molecular Weight(MW) | 35110 Da |
| Function | Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development |
| Tissue Specificity | Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in the brain especially in the hippocampus |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (By similarity). Membrane raft. Cell junction, synapse, postsynaptic cell membrane (By similarity) |
| Entrez Gene | 23017 |
|---|---|
| Nucleotide Accession | NP_036438.2 |
Application
FAIM2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the FAIM2 antibody detected the FAIM2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
