Application
FAM125A Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the FAM125A antibody detected the FAM125A protein (arrow).| Product Name | FAM125A Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FAM125A; CFBP; Multivesicular body subunit 12A; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; Protein FAM125A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CFBP FAM125A |
|---|---|
| Alternative Names | FAM125A CFBP Multivesicular body subunit 12A CIN85/CD2AP family-binding protein ESCRT-I complex subunit MVB12A Protein FAM125A |
| Molecular Weight(MW) | 28783 Da |
| Function | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down- regulation of EGF receptor |
| Tissue Specificity | Ubiquitously expressed except in skeletal muscle |
| Cellular Localization | Cytoplasm. Nucleus. Endosome. Cytoplasm, cytoskeleton, centrosome. Late endosome membrane; Peripheral membrane protein (Probable). Note=Colocalizes with F-actin. Some fraction may be nuclear |
| Entrez Gene | 93343 |
|---|---|
| Nucleotide Accession | NP_612410.1 |
Application
FAM125A Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the FAM125A antibody detected the FAM125A protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
