FAM82A2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FAM82A2 antibody detected the FAM82A2 protein (arrow).
FAM82A2; FAM82C; PTPIP51; Regulator of microtubule dynamics protein 3; Cerebral protein 10; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase-interacting protein 51; TCPTP-interacting protein 51
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
FAM82A2 FAM82C PTPIP51
Alternative Names
FAM82A2 FAM82C PTPIP51 Regulator of microtubule dynamics protein 3 Cerebral protein 10 Protein FAM82A2 Protein FAM82C Protein tyrosine phosphatase-interacting protein 51 TCPTP-interacting protein 51
Molecular Weight(MW)
52118 Da
Function
Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes Overexpression induces apoptosis
Tissue Specificity
Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system (at protein level). Widely expressed
Cellular Localization
Mitochondrion membrane; Single-pass membrane protein. Mitochondrion outer membrane. Cytoplasm. Nucleus Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles
FAM82A2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the FAM82A2 antibody detected the FAM82A2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.