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FANCC Antibody (C-term)

Catalog Number:OM232883
OM232883
Discount Price
OM232883-100ul
1~2 Week
100ul
OM232883-50ul
50ul
OM232883-20ul
20ul
1~2 Week
Product Profile
Product Name FANCC Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias FANCC; FAC; FACC; Fanconi anemia group C protein
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFCIF
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms FAC
FACC
Alternative Names FANCC
FAC
FACC
Fanconi anemia group C protein
Molecular Weight(MW) 63429 Da
Function DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1
Tissue Specificity Ubiquitous.
Cellular Localization Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic
Database Links
Entrez Gene 2176
Application

Application

FANCC Antibody (C-term) western blot analysis in HL-60,HepG2 cell line lysates (35ug/lane).This demonstrates the FANCC antibody detected the FANCC protein (arrow).

Application

FANCC Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FANCC Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

FANCC Antibody (C-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

Confocal immunofluorescent analysis of FANCC Antibody (C-term) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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