Application
FANCL Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the FANCL antibody detected the FANCL protein (arrow).| Product Name | FANCL (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FANCL; PHF9; E3 ubiquitin-protein ligase FANCL; Fanconi anemia group L protein; Fanconi anemia-associated polypeptide of 43 kDa |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PHF9 |
|---|---|
| Alternative Names | FANCL PHF9 E3 ubiquitin-protein ligase FANCL Fanconi anemia group L protein Fanconi anemia-associated polypeptide of 43 kDa |
| Molecular Weight(MW) | 42905 Da |
| Function | Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth |
| Tissue Specificity | This FANCL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-302 amino acids from the C-terminal region of human FANCL. |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 55120 |
|---|---|
| Nucleotide Accession | NP_001108108.1 |
Application
FANCL Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the FANCL antibody detected the FANCL protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
