Application
FBLN1 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the FBLN1 antibody detected the FBLN1 protein (arrow).Application
FBLN1 Antibody (C-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the FBLN1 antibody detected the FBLN1 protein (arrow).Application
FBLN1 Antibody (C-term) (AP14671b)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FBLN1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | FBLN1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FBLN1; Fibulin-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FBLN1 Fibulin-1 |
|---|---|
| Molecular Weight(MW) | 77214 Da |
| Function | Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP |
| Tissue Specificity | Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Entrez Gene | 2192 |
|---|---|
| Nucleotide Accession | NP_001987.2 NP_006477.2 |
Application
FBLN1 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the FBLN1 antibody detected the FBLN1 protein (arrow).
Application
FBLN1 Antibody (C-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the FBLN1 antibody detected the FBLN1 protein (arrow).
Application
FBLN1 Antibody (C-term) (AP14671b)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FBLN1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
