Application
Western blot analysis of FBXL7 Antibody (N-term) in mouse heart tissue lysates (35ug/lane). FBXL7 (arrow) was detected using the purified Pab.Application
FBXL7 Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.Application
Western blot analysis of FBXL7 (arrow) using rabbit polyclonal FBXL7 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FBXL7 gene.| Product Name | FBXL7 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FBXL7; FBL6; FBL7; KIAA0840; F-box/LRR-repeat protein 7; F-box and leucine-rich repeat protein 7; F-box protein FBL6/FBL7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FBL6 FBL7 KIAA0840 |
|---|---|
| Alternative Names | FBXL7 FBL6 FBL7 KIAA0840 F-box/LRR-repeat protein 7 F-box and leucine-rich repeat protein 7 F-box protein FBL6/FBL7 |
| Molecular Weight(MW) | 54575 Da |
| Function | Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest (By similarity) |
| Tissue Specificity | This FBXL7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98~127 amino acids from the N-terminal region of human FBXL7. |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome (By similarity). Note=Localizes to the centrosome during spindle formation (By similarity) |
| Entrez Gene | 23194 |
|---|
Application
Western blot analysis of FBXL7 Antibody (N-term) in mouse heart tissue lysates (35ug/lane). FBXL7 (arrow) was detected using the purified Pab.
Application
FBXL7 Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application
Western blot analysis of FBXL7 (arrow) using rabbit polyclonal FBXL7 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FBXL7 gene.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
