Application
FBXO22 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the FBXO22 antibody detected the FBXO22 protein (arrow).| Product Name | FBXO22 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FBX22 |
|---|---|
| Alternative Names | FBXO22 FBX22 F-box only protein 22 F-box protein FBX22p44 |
| Molecular Weight(MW) | 44508 Da |
| Function | Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function |
| Tissue Specificity | Predominantly expressed in liver, also enriched in cardiac muscle |
| Cellular Localization | Cytoplasm, myofibril, sarcomere, Z line (By similarity) |
| Entrez Gene | 26263 |
|---|---|
| Nucleotide Accession | NP_036302.1 |
Application
FBXO22 Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the FBXO22 antibody detected the FBXO22 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
