Application
FBXW8 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the FBXW8 antibody detected the FBXW8 protein (arrow).Application
FBXW8 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the FBXW8 antibody detected the FBXW8 protein (arrow).Application
FBXW8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXW8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
FBXW8 Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | FBXW8 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FBW6, FBW8, FBX29, FBXO29, FBXW6 |
|---|---|
| Alternative Names | FBXW8 FBW6 FBW8 FBX29 FBXO29 FBXW6 F-box/WD repeat-containing protein 8 F-box and WD-40 domain-containing protein 8 F-box only protein 29 |
| Molecular Weight(MW) | 67394 Da |
| Function | Substrate-recognition component of a SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity) |
| Tissue Specificity | This FBXW8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-303 amino acids from the Central region of human FBXW8. |
| Entrez Gene | 26259 |
|---|---|
| Nucleotide Accession | NP_036306.1 |
Application
FBXW8 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the FBXW8 antibody detected the FBXW8 protein (arrow).
Application
FBXW8 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the FBXW8 antibody detected the FBXW8 protein (arrow).
Application
FBXW8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXW8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
FBXW8 Antibody (Center) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
