Application
FBXW10 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the FBXW10 antibody detected the FBXW10 protein (arrow).Application
FBXW10 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXW10 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
FBXW10 Antibody (C-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | FBXW10 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FBXW10 F-box/WD repeat-containing protein 10 F-box and WD-40 domain-containing protein 10 Ubiquitin ligase-specificity factor |
|---|---|
| Molecular Weight(MW) | 119846 Da |
| Function | Probable substrate-recognition component of a SCF (SKP1- CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1 |
| Tissue Specificity | This FBXW10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 765-795 amino acids from the C-terminal region of human FBXW10. |
| Entrez Gene | 10517 |
|---|---|
| Nucleotide Accession | NP_113644.3 |
Application
FBXW10 Antibody (C-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the FBXW10 antibody detected the FBXW10 protein (arrow).
Application
FBXW10 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXW10 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
FBXW10 Antibody (C-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
