Application
A. Western blot analysis on Daudi cell lysates using anti-Phospho-Fc gamma RIIb (py292) RabMAb (Cat. #AJ1287c), 1:100,000 dilution. Cells were either (A) untreated (B) treated with pervanadate.| Product Name | Fc-gamma (RIIb/CD32) Antibody Phospho-pY292 |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification | p-RIIb/CD32 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP926Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50000~100000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD32, FCG2, IGFR2 |
|---|---|
| Alternative Names | FCGR2B CD32 FCG2 IGFR2 Low affinity immunoglobulin gamma Fc region receptor II-b CDw32 |
| Molecular Weight(MW) | 34044 Da |
| Function | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis |
| Tissue Specificity | Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 2213 |
|---|
Application
A. Western blot analysis on Daudi cell lysates using anti-Phospho-Fc gamma RIIb (py292) RabMAb (Cat. #AJ1287c), 1:100,000 dilution. Cells were either (A) untreated (B) treated with pervanadate.| Application Notes | WB:1:50000~100000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
