Application
FCGR2B Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the FCGR2B antibody detected the FCGR2B protein (arrow).| Product Name | FCGR2B Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD32, FCG2, IGFR2 |
|---|---|
| Alternative Names | FCGR2B CD32 FCG2 IGFR2 Low affinity immunoglobulin gamma Fc region receptor II-b CDw32 Fc-gamma RII-b CD_antigen=CD32 Flags: Precursor |
| Molecular Weight(MW) | 34044 Da |
| Function | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis |
| Tissue Specificity | Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 2213 |
|---|---|
| Nucleotide Accession | NP_003992.3 NP_001002273.1 NP_001177757.1 NP_001002274.1 |
Application
FCGR2B Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the FCGR2B antibody detected the FCGR2B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
