Application
Western blot analysis of FCGR3B Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). FCGR3B (arrow) was detected using the purified Pab.| Product Name | FCGR3B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CD16B, FCG3, FCGR3, IGFR3 |
|---|---|
| Alternative Names | FCGR3B CD16B FCG3 FCGR3 IGFR3 Low affinity immunoglobulin gamma Fc region receptor III-B Fc-gamma RIII-beta FcR-10 IgG Fc receptor III-1 CD_antigen=CD16b Flags: Precursor |
| Molecular Weight(MW) | 26216 Da |
| Function | Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils |
| Tissue Specificity | Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Secreted after cleavage |
| Entrez Gene | 2215 |
|---|
Application
Western blot analysis of FCGR3B Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). FCGR3B (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
