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FFR Antibody (Center)

Catalog Number:OM233088
OM233088
Discount Price
OM233088-100ul
1~2 Week
100ul
OM233088-50ul
50ul
OM233088-20ul
20ul
1~2 Week
Product Profile
Product Name FFR Antibody (Center)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms ANG2, C11orf2, C11orf3, FFR
Alternative Names FFR
ANG2
C11orf2
C11orf3
Protein fat-free homolog
Another new gene 2 protein
Molecular Weight(MW) 86042 Da
Function Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi networkl (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN
Tissue Specificity This FFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-292 amino acids from the Central region of human FFR.
Cellular Localization Golgi apparatus, trans-Golgi network.
Database Links
Entrez Gene 738
Nucleotide Accession NP_037397.2
Application

Application

FFR Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the FFR antibody detected the FFR protein (arrow).

Application

FFR antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FFR antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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