FGD4 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the FGD4 antibody detected the FGD4 protein (arrow).
FGD4 FRABP ZFYVE6 FYVE RhoGEF and PH domain-containing protein 4 Actin filament-binding protein frabin FGD1-related F-actin-binding protein Zinc finger FYVE domain-containing protein 6
Molecular Weight(MW)
86626 Da
Function
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape Activates MAPK8 (By similarity)
Tissue Specificity
Expressed in different tissues, including brain, cerebellum, peripheral nerve, skeletal muscle, heart, uterus, placenta and testis
Cellular Localization
Cytoplasm, cytoskeleton (By similarity). Cell projection, filopodium (By similarity). Note=Concentrated in filopodia and poorly detected at lamellipodia. Binds along the sides of actin fibers (By similarity)
FGD4 Antibody (N-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the FGD4 antibody detected the FGD4 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.