Application
Western blot analysis of FGF19 (arrow) using rabbit polyclonal FGF19 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FGF19 gene.| Product Name | FGF19 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FGF19 Fibroblast growth factor 19 |
|---|---|
| Molecular Weight(MW) | 24003 Da |
| Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4 |
| Tissue Specificity | Expressed in fetal brain, cartilage, retina, and adult gall bladder |
| Cellular Localization | Secreted. |
| Entrez Gene | 9965 |
|---|---|
| Nucleotide Accession | NP_005108.1 |
Application
Western blot analysis of FGF19 (arrow) using rabbit polyclonal FGF19 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FGF19 gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
