Application
FIG4 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the FIG4 antibody detected the FIG4 protein (arrow).Application
FIG4 Antibody (C-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the FIG4 antibody detected the FIG4 protein (arrow).| Product Name | FIG4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0274, SAC3 |
|---|---|
| Alternative Names | FIG4 KIAA0274 SAC3 Polyphosphoinositide phosphatase Phosphatidylinositol 3 5-bisphosphate 5-phosphatase SAC domain-containing protein 3 |
| Molecular Weight(MW) | 103635 Da |
| Function | The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes |
| Tissue Specificity | This FIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 845-874 amino acids from the C-terminal region of human FIG4. |
| Cellular Localization | Endosome membrane. Note=Localization requires VAC14 and PIKFYVE |
| Entrez Gene | 9896 |
|---|---|
| Nucleotide Accession | NP_055660.1 |
Application
FIG4 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the FIG4 antibody detected the FIG4 protein (arrow).
Application
FIG4 Antibody (C-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the FIG4 antibody detected the FIG4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
