Application
FIL1L Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the FIL1L antibody detected the FIL1L protein (arrow).| Product Name | FIL1L Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | COL4A3BPIP, DOC1, GIP90 |
|---|---|
| Alternative Names | FILIP1L COL4A3BPIP DOC1 GIP90 Filamin A-interacting protein 1-like 130 kDa GPBP-interacting protein 90 kDa GPBP-interacting protein Protein down-regulated in ovarian cancer 1 |
| Molecular Weight(MW) | 130382 Da |
| Function | Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor- associated vasculature |
| Tissue Specificity | Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer |
| Cellular Localization | Cytoplasm. Membrane. Nucleus. |
| Entrez Gene | 11259 |
|---|---|
| Nucleotide Accession | NP_001035924.1 |
Application
FIL1L Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the FIL1L antibody detected the FIL1L protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
