Application
Western blot analysis of FIP1L1 Antibody (C-term) in WiDr cell line lysates (35ug/lane). FIP1L1 (arrow) was detected using the purified Pab.| Product Name | FIP1L1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FIP1L1; FIP1; RHE; Pre-mRNA 3'-end-processing factor FIP1; FIP1-like 1 protein; Factor interacting with PAP; Rearranged in hypereosinophilia |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FIP1 RHE |
|---|---|
| Alternative Names | FIP1L1 FIP1 RHE Pre-mRNA 3'-end-processing factor FIP1 FIP1-like 1 protein Factor interacting with PAP Rearranged in hypereosinophilia |
| Molecular Weight(MW) | 66526 Da |
| Function | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre- mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex |
| Tissue Specificity | This FIP1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504~534 amino acids from the C-terminal region of human FIP1L1. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 81608 |
|---|
Application
Western blot analysis of FIP1L1 Antibody (C-term) in WiDr cell line lysates (35ug/lane). FIP1L1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
