Application
FNBP1L Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the FNBP1L antibody detected the FNBP1L protein (arrow).| Product Name | FNBP1L Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FNBP1L; C1orf39; TOCA1; Formin-binding protein 1-like; Transducer of Cdc42-dependent actin assembly protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C1orf39 TOCA1 |
|---|---|
| Alternative Names | FNBP1L C1orf39 TOCA1 Formin-binding protein 1-like Transducer of Cdc42-dependent actin assembly protein 1 |
| Molecular Weight(MW) | 69977 Da |
| Function | Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens |
| Tissue Specificity | This FNBP1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-377 amino acids from the Central region of human FNBP1L. |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Cytoplasm, cell cortex (By similarity). Cytoplasmic vesicle (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) |
| Entrez Gene | 54874 |
|---|---|
| Nucleotide Accession | NP_001157945.1 NP_001020119.1 |
Application
FNBP1L Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the FNBP1L antibody detected the FNBP1L protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
