Application
FNIP2 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the FNIP2 antibody detected the FNIP2 protein (arrow).Application
FNIP2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FNIP2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
FNIP2 Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | FNIP2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FNIP2; FNIPL; KIAA1450; MAPO1; Folliculin-interacting protein 2; FNIP1-like protein; O6-methylguanine-induced apoptosis 1 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FNIPL KIAA1450 MAPO1 |
|---|---|
| Alternative Names | FNIP2 FNIPL KIAA1450 MAPO1 Folliculin-interacting protein 2 FNIP1-like protein O6-methylguanine-induced apoptosis 1 protein |
| Molecular Weight(MW) | 122115 Da |
| Function | May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1 |
| Tissue Specificity | Widely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenta and pancreas. Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue. Higher levels detected in oncocytoma than in normal kidney |
| Cellular Localization | Cytoplasm. Note=Co-localizes with FLCN in the cytoplasm |
| Entrez Gene | 57600 |
|---|---|
| Nucleotide Accession | NP_065891.1 |
Application
FNIP2 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the FNIP2 antibody detected the FNIP2 protein (arrow).
Application
FNIP2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FNIP2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
FNIP2 Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
