Application
FRS2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FRS2 antibody detected the FRS2 protein (arrow).| Product Name | FRS2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FRS2; Fibroblast growth factor receptor substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | FRS2 Fibroblast growth factor receptor substrate 2 FGFR-signaling adaptor SNT Suc1-associated neurotrophic factor target 1 |
|---|---|
| Molecular Weight(MW) | 57029 Da |
| Function | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1 Modulates signaling via SHC1 by competing for a common binding site on NTRK1 |
| Tissue Specificity | Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis |
| Cellular Localization | Endomembrane system. Note=Cytoplasmic, membrane-bound |
| Entrez Gene | 10818 |
|---|---|
| Nucleotide Accession | NP_006645.3 |
Application
FRS2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FRS2 antibody detected the FRS2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
