Application
FSTL3 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FSTL3 antibody detected the FSTL3 protein (arrow).Application
FSTL3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FSTL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | FSTL3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FLRG |
|---|---|
| Alternative Names | FSTL3 FLRG Follistatin-related protein 3 Follistatin-like protein 3 Follistatin-related gene protein |
| Molecular Weight(MW) | 27663 Da |
| Function | Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10 |
| Tissue Specificity | Expressed in a wide range of tissues. |
| Cellular Localization | Isoform 1: Secreted. |
| Entrez Gene | 10272 |
|---|---|
| Nucleotide Accession | NP_005851.1 |
Application
FSTL3 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FSTL3 antibody detected the FSTL3 protein (arrow).
Application
FSTL3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FSTL3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
