Application
FXYD5 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FXYD5 antibody detected the FXYD5 protein (arrow).Application
FXYD5 Antibody (Center) (AP14909c)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FXYD5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | FXYD5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DYSAD, IWU1 |
|---|---|
| Alternative Names | FXYD5 DYSAD IWU1 FXYD domain-containing ion transport regulator 5 Dysadherin |
| Molecular Weight(MW) | 19472 Da |
| Function | Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis |
| Tissue Specificity | This FXYD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 amino acids from the Central region of human FXYD5. |
| Cellular Localization | Membrane; Single-pass type I membrane protein (Potential) |
| Entrez Gene | 53827 |
|---|---|
| Nucleotide Accession | NP_001158077.1 NP_659003.1 |
Application
FXYD5 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FXYD5 antibody detected the FXYD5 protein (arrow).
Application
FXYD5 Antibody (Center) (AP14909c)immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FXYD5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
