G2E3 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the G2E3 antibody detected the G2E3 protein (arrow).
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates Essential in early embryonic development to prevent apoptotic death
Tissue Specificity
Predominantly expressed in brain, liver, kidney, testes and ovary
Cellular Localization
Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage
G2E3 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the G2E3 antibody detected the G2E3 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.