Application
Western blot analysis of Gab1 (arrow) using rabbit polyclonal Gab1 Antibody (Y659) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GAB1 gene (Lane 2) (Origene Technologies).Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Gab1 Antibody (Y659) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | Gab1 Antibody (Y659) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GAB1 GRB2-associated-binding protein 1 GRB2-associated binder 1 Growth factor receptor bound protein 2-associated protein 1 |
|---|---|
| Molecular Weight(MW) | 76616 Da |
| Function | Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR) |
| Tissue Specificity | This Gab1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 645~675 amino acids surrounding Y659 of human GAB1. |
| Entrez Gene | 2549 |
|---|
Application
Western blot analysis of Gab1 (arrow) using rabbit polyclonal Gab1 Antibody (Y659) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GAB1 gene (Lane 2) (Origene Technologies).
Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Gab1 Antibody (Y659) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
