Application
A. Western blot analysis of anti-Gab2 RabMAb (Cat. #AJ1309a), dilution 1:500. A: K562 B: MCF-7Application
B. Immunofluorescent staining of PC-12 cells using anti-Gab-2 RabMAb (Cat. #AJ1309a).| Product Name | Gab2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP369Y |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:1000~10000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0571 |
|---|---|
| Alternative Names | GAB2 KIAA0571 GRB2-associated-binding protein 2 Growth factor receptor bound protein 2-associated protein 2 GRB2-associated binder 2 pp100 |
| Molecular Weight(MW) | 74458 Da |
| Function | Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis |
| Tissue Specificity | A synthetic peptide corresponding to residues in human Gab2 was used as immunogen. This antibody is predicted to detect the splice isoform 2 based on sequence homology. |
| Cellular Localization | Cytoplasm. Cell membrane. |
| Entrez Gene | 9846 |
|---|
Application
A. Western blot analysis of anti-Gab2 RabMAb (Cat. #AJ1309a), dilution 1:500. A: K562 B: MCF-7
Application
B. Immunofluorescent staining of PC-12 cells using anti-Gab-2 RabMAb (Cat. #AJ1309a).| Application Notes | WB:1:1000~10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
