Application
GABRB2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GABRB2 antibody detected the GABRB2 protein (arrow).| Product Name | GAB_2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GABRB2 Gamma-aminobutyric acid receptor subunit beta-2 GABA(A) receptor subunit beta-2 |
|---|---|
| Molecular Weight(MW) | 59150 Da |
| Function | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel |
| Tissue Specificity | Isoform 1 and isoform 2 show reduced expression in schizophrenic brain. Isoform 3 shows increased expression in schizophrenic and bipolar disorder brains while isoform 4 shows reduced expression |
| Cellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein |
| Entrez Gene | 2561 |
|---|---|
| Nucleotide Accession | NP_068711.1 NP_000804.1 |
Application
GABRB2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GABRB2 antibody detected the GABRB2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
