Application
A. Western blot analysis on fetal brain lysate using anti-gamma Synuclein RabMAb (Cat. #AJ1313a), dilution 1:2000.Application
B. Immunohistochemical staining of paraffin-embedded human brain using anti-gamma Synuclein RabMAb (Cat. #AJ1313a).| Product Name | Gamma Synuclein (SR) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1539Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~10000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BCSG1, PERSYN, PRSN |
|---|---|
| Alternative Names | SNCG BCSG1 PERSYN PRSN Gamma-synuclein Persyn Breast cancer-specific gene 1 protein Synoretin |
| Molecular Weight(MW) | 13331 Da |
| Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity) May also function in modulating the keratin network in skin Activates the MAPK and Elk-1 signal transduction pathway (By similarity) |
| Tissue Specificity | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung |
| Cellular Localization | Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle |
| Entrez Gene | 6623 |
|---|
Application
A. Western blot analysis on fetal brain lysate using anti-gamma Synuclein RabMAb (Cat. #AJ1313a), dilution 1:2000.
Application
B. Immunohistochemical staining of paraffin-embedded human brain using anti-gamma Synuclein RabMAb (Cat. #AJ1313a).| Application Notes | WB:1:1000~10000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
