Application
Western blot analysis of GAN antibody (Center H205) in 293 cell line lysates (35ug/lane). GAN (arrow) was detected using the purified Pab.Application
GAN Antibody (Center H205) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GAN Antibody (Center H205) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | GAN Antibody (Center H205) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GAN1, KLHL16 |
|---|---|
| Alternative Names | GAN GAN1 KLHL16 Gigaxonin Kelch-like protein 16 |
| Molecular Weight(MW) | 67638 Da |
| Function | Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival |
| Tissue Specificity | Expressed in brain, heart and muscle. |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton. |
| Entrez Gene | 8139 |
|---|
Application
Western blot analysis of GAN antibody (Center H205) in 293 cell line lysates (35ug/lane). GAN (arrow) was detected using the purified Pab.
Application
GAN Antibody (Center H205) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GAN Antibody (Center H205) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
