Application
GAS2 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the GAS2 antibody detected the GAS2 protein (arrow).| Product Name | GAS2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GAS2 Growth arrest-specific protein 2 |
|---|---|
| Molecular Weight(MW) | 34945 Da |
| Function | May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity) |
| Tissue Specificity | Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen |
| Cellular Localization | Cytoplasm, cytoskeleton (By similarity). Membrane; Peripheral membrane protein (By similarity) Note=Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth- arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles (By similarity) |
| Entrez Gene | 2620 |
|---|---|
| Nucleotide Accession | NP_001137302.1 |
Application
GAS2 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the GAS2 antibody detected the GAS2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
