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GCC2 Antibody (C-term)

Catalog Number:OM233855
OM233855
Discount Price
OM233855-100ul
1~2 Week
100ul
OM233855-50ul
50ul
OM233855-20ul
20ul
1~2 Week
Product Profile
Product Name GCC2 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms KIAA0336, RANBP2L4
Alternative Names GCC2
KIAA0336
RANBP2L4
GRIP and coiled-coil domain-containing protein 2
185 kDa Golgi coiled-coil protein
CLL-associated antigen KW-11
CTCL tumor antigen se1-1
Ran-binding protein 2-like 4
Renal carcinoma antigen NY-REN-53
Molecular Weight(MW) 195910 Da
Function Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2
Tissue Specificity Ubiquitous.
Cellular Localization Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein
Database Links
Entrez Gene 9648
Nucleotide Accession NP_852118.1
Application

Application

GCC2 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (15ug/lane).This demonstrates the GCC2 antibody detected GCC2 protein (arrow).

Application

GCC2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GCC2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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