Application
Western blot analysis of anti-GCN5 Antibody (N-term) in 293 cell line lysates (35ug/lane). GCN5(arrow) was detected using the purified Pab (1:60 dilution).| Product Name | GCN5 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | GCN5, GCN5L2, HGCN5 |
|---|---|
| Alternative Names | KAT2A GCN5 GCN5L2 HGCN5 Histone acetyltransferase KAT2A General control of amino acid synthesis protein 5-like 2 Histone acetyltransferase GCN5 Lysine acetyltransferase 2A STAF97 |
| Molecular Weight(MW) | 93926 Da |
| Function | Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 |
| Tissue Specificity | Expressed in all tissues tested, with most abundant expression in ovary |
| Cellular Localization | Nucleus. |
Application
Western blot analysis of anti-GCN5 Antibody (N-term) in 293 cell line lysates (35ug/lane). GCN5(arrow) was detected using the purified Pab (1:60 dilution).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
